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Additionally, idebenone prevents excessive autophagy and regulates the AMPK-mTOR pathway, which is crucial in MI pathophysiology

While pineal melatonin regulates the circadian rhythms, extra pineal melatonin performs various functions beyond its primary role, which includes acting as an antioxidant, stimulating the production of endogenous antioxidant enzymes, scavenging free radicals, and playing a homeostatic role within mitochondria (ArandaMartnez et al

Instead, tamoxifen binding to ABCB1 blocks its ability to transport other xenobiotics 72

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Prcautions d'emploi Une surveillance hmatologique et neurologique rgulire doit tre mene tout au long du traitement